Central Massachusetts Vacations from $184

Book a Hotel + Flight or Car together to unlock savings

Your Central Massachusetts Vacation

Make planning your next getaway a piece of cake with a Central Massachusetts vacation package. Whether it's the history, cuisine or something else entirely that lures you to this destination, our packages will help you discover it all. Start your trip to Central Massachusetts with some time exploring Marlborough visiting popular sights like Apex Entertainment Center and Tower Hill Botanic Garden. Sturbridge is another top city that lures crowds from near and far. Old Sturbridge Village and Wells State Park are two of the leading places to see here. Expedia is a one-stop shop when it comes to organizing your Central Massachusetts vacation. From flights and accommodations, to rental cars and activities, we know how to create a travel experience like no other.

The Latest Central Massachusetts vacation packages

Price found within the past 48 hours. Click for updated prices.
The Revolution Hotel
Boston Lodge and Suites
The Charles Hotel
Club Quarters Hotel Faneuil Hall, Boston
YOTEL Boston
Don't see what you're looking for?
See all available trips from Columbus to Central Massachusetts
View all trips

Where to stay in Central Massachusetts

Find the best Central Massachusetts areas and neighborhoods for the activities you enjoy most. Learn more about Central Massachusetts

Discover the most popular places to visit in Central Massachusetts

What to do in Central Massachusetts

Central Massachusetts Hotel Deals

Motel 6 Framingham, MA - Boston West

Motel 6 Framingham, MA - Boston West

2 out of 5
1668 Worcester Rd, Framingham, MA
Fully refundable
$97 nightly
The price is $102 total per night from Nov 2 to Nov 3
$102 total
Nov 2 - Nov 3
Total with taxes and fees
6.6/10 (1,045 reviews)
"There's not much to this property. Not much room to park and nowhere to walk my dog. A few +/- of the places is it's got clean rooms and it's right off the highway. There's both a Dunkin & BP if you need to hit the road first thing in the morning. But! The highway is noisy and there's a loud freight ..."

Reviewed on Oct 3, 2025

Motel 6 Framingham, MA - Boston West
The Verve Hotel Boston Natick, Tapestry Collection by Hilton

The Verve Hotel Boston Natick, Tapestry Collection by Hilton

3.5 out of 5
1360 Worcester St, Natick, MA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $133 total per night from Oct 12 to Oct 13
$133 total
Oct 12 - Oct 13
Total with taxes and fees
8.4/10 Very Good! (1,001 reviews)
"All good"

Reviewed on Oct 1, 2025

The Verve Hotel Boston Natick, Tapestry Collection by Hilton
DoubleTree by Hilton Hotel Boston - Westborough

DoubleTree by Hilton Hotel Boston - Westborough

4 out of 5
5400 Computer Dr, Westborough, MA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $133 total per night from Nov 2 to Nov 3
$133 total
Nov 2 - Nov 3
Total with taxes and fees
8.6/10 Excellent! (1,049 reviews)
"Very quick and easy check in! Room was in very nice shape and really liked the free cookie they give you just makes you feel at home!"

Reviewed on Sep 29, 2025

DoubleTree by Hilton Hotel Boston - Westborough
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Central Massachusetts Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Logan Intl. Airport (BOS)

More vacations you might like

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.